CD249 Polyclonal Antibody
Ucallm_WP15633-50
Price range: $268.00 through $328.00
Product details
Background:
catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide., cofactor:Binds 1 zinc ion per subunit., function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells., similarity:Belongs to the peptidase M1 family., subunit:Homodimer; disulfide-linked., tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.,
Specifications
| Size | 50μL/100μL |
| Target | CD249 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 110kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human ENPEP. AA range:671-720 |
| Specificity | CD249 Polyclonal Antibody detects endogenous levels of CD249 protein. |
| Gene Name | ENPEP |
| Protein Name | Glutamyl aminopeptidase |
| Other Name | ENPEP; / Glutamyl aminopeptidase; / EAP; / Aminopeptidase A; / AP-A; / Differentiation antigen gp160; / CD249 |
| Species | Human |
| Gene ID | 2028 |
| Uniprot | Q07075, |
| Species.1 | Mouse |
| Gene ID.1 | 13809 |
| Uniprot.1 | P16406, |
| Species.2 | Rat |
| Gene ID.2 | 64017 |
| Uniprot.2 | P50123 |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein. |
| Tissue Expression | Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Renin-angiotensin system |
| Research Areas | >>Renin-angiotensin system |
| Function | Catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,Function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues., |
Please login to post questions
Related products
