CD2BP2 Polyclonal Antibody
Ucallm_WP11492-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],
Specifications
| Size | 50μL/100μL |
| Target | CD2BP2 |
| Reactivity | Human, Monkey |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 50kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150 |
| Specificity | CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein. |
| Gene Name | CD2BP2 |
| Protein Name | CD2 antigen cytoplasmic tail-binding protein 2 |
| Other Name | CD2BP2; / KIAA1178; / CD2 antigen cytoplasmic tail-binding protein 2; / CD2 cytoplasmic domain-binding protein 2; / CD2 tail-binding protein 2 |
| Species | Human |
| Gene ID | 10421 |
| Uniprot | O95400, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CWK3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm. Nucleus. Predominantly nuclear. |
| Tissue Expression | Aorta,Brain,Epithelium,Liver,Lung, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain., |
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