Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010],
| Specification | 50μL;100μL |
| Target | CD31 |
| Reactivity | Human |
| Applications | WB, IP |
| MW(Calculated) | |
| MW(Observed) | 130kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000 |
| Composition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Puity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Purified recombinant human CD31 protein fragments expressed in E.coli. |
| Sequence | |
| Specificity | This antibody detects endogenous levels of CD31 and does not cross-react with related proteins. |
| Gene Name | pecam1 |
| Protein Name | |
| Alias | Adhesion molecule;CD31;CD31 antigen;CD31 EndoCAM;Endocam;FLJ34100;FLJ58394;GPIIA;GPIIA';PECA1;PECA1_HUMAN;Pecam 1;PECAM 1 CD31 EndoCAM;PECAM;PECAM-1;Pecam1;Platelet endothelial cell adhesion molecule;Platelet/endothelial cell adhesion molecule 1;Platelet/endothelial cell adhesion molecule. |
| Organism-1 | Human |
| Gene ID-1 | 18613 |
| SwissProt-1 | P16284 |
| Organism-2 | Mouse |
| Gene ID-2 | |
| SwissProt-2 | Q08481 |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Cell membrane ; Single-pass type I membrane protein . Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation. .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Membrane raft . Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. .; [Isoform Delta15]: Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. |
