Name: CD32-B/C Polyclonal Antibody
SKU: WP15318
Price: 268 USD
Availability: InStock

CD32-B/C Polyclonal Antibody

Ucallm_WP15318-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP15318-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

Low affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Specifications

Size	50μL/100μL
Target	CD32
Reactivity	Human
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	35kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human FCGR2B/C. AA range:141-190
Specificity	CD32-B/C Polyclonal Antibody detects endogenous levels of CD32-B/C protein.
Gene Name	FCGR2B/FCGR2C
Protein Name	Low affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c
Other Name	FCGR2B; / CD32; / FCG2; / IGFR2; / Low affinity immunoglobulin gamma Fc region receptor II-b; / IgG Fc receptor II-b; / CDw32; / Fc-gamma RII-b; / Fc-gamma-RIIb; / FcRII-b; / CD32; / FCGR2C; / CD32; / FCG2; / IGFR2; / Low affinity immunoglobulin gamma Fc region receptor II-c; / IgG Fc receptor II-c; / CDw32; / Fc-gamma RII-c; / Fc-gamma-RIIc; / FcRII-c; / CD32
Species	Human
Gene ID	2213
Uniprot	P31994
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cell membrane; Single-pass type I membrane protein.
Tissue Expression	Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Phagosome;Organismal Systems >> Immune system >> B cell receptor signaling pathway;Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis;Organismal Systems >> Development and regeneration >> Osteoclast differentiation
Research Areas	>>Phagosome; / >>Osteoclast differentiation; / >>B cell receptor signaling pathway; / >>Fc gamma R-mediated phagocytosis; / >>Staphylococcus aureus infection; / >>Tuberculosis; / >>Measles
Function	immune response,