SKU: WM1386 Categories: ,

CD44 [ABT147] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1386-50
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Product details

Background:
CD44 is a cell surface receptor, which belongs to the family of cell adhesion molecules that mediate cell-to-cell and cell-to-matrix adhesion, and interacts with cytoskeletal proteins. CD44 is widely expressed in hematopoietic cells and mesodermal cells and is a marker of these cells. Studies have shown that the loss of CD44 expression is related to invasion, metastasis and progression of lung cancer, prostate cancer, breast cancer, ovarian cancer and malignant melanoma.

Specifications

Specification50μL;100μL
TargetCD44
ReactivityHuman
ApplicationsIHC, WB, IF, ELISA
MW(Calculated)81kD
MW(Observed)81kD
Host SpeciesMouse
IsotypeIgG2b, Kappa
Conjugate
ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification ProcessProtein G
Puity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberABT147
ImmunogenSynthesized peptide derived from human CD44 AA range: 100-200
Sequence
SpecificityThe antibody can specifically recognize human CD44 protein. In western blotting of Hela cell lysate, the antibody can label a 81 kDa band corresponding to CD44.
Gene NameCD44 LHR MDU2 MDU3 MIC4
Protein NameCD44
AliasLHR;BA-1;CD 44;CD44;CD44 antigen;CD44 molecule;Indian blood group;CD44 molecule;CD44_HUMAN;CDw44;CDW44 antigen;Cell surface glycoprotein CD44;chondroitin sulfate proteoglycan 8;CSPG8;ECMR-III;Epican;Extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HCELL;hematopoietic cell E- and L-selectin ligand;Heparan sulfate proteoglycan;Hermes antigen;homing function and Indian blood group system;HSA;HUTCH-I;HUTCH1;HUTCHI;Hyaluronate receptor;IN;INLU-related p80 Glycoprotein;MC56;MDU2;MDU3;MGC10468;MIC4;MUTCH I;MUTCH1;PGP-1;PGP-I;PGP1;Phagocytic glycoprotein 1;Phagocytic glycoprotein I;Soluble CD44
Organism-1Human
Gene ID-1960
SwissProt-1P16070
Organism-2
Gene ID-2
SwissProt-2
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationMembranous
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