CD9 Polyclonal Antibody
Ucallm_WP11521-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011],
Specifications
| Size | 50μL/100μL |
| Target | CD9 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 25kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD9. AA range:101-150 |
| Specificity | CD9 Polyclonal Antibody detects endogenous levels of CD9 protein. |
| Gene Name | CD9 |
| Protein Name | CD9 antigen |
| Other Name | CD9; / MIC3; / TSPAN29; / GIG2; / CD9 antigen; / 5H9 antigen; / Cell growth-inhibiting gene 2 protein; / Leukocyte antigen MIC3; / Motility-related protein; / MRP-1; / Tetraspanin-29; / Tspan-29; / p24; / CD antigen CD9 |
| Species | Human |
| Gene ID | 928 |
| Uniprot | P21926, |
| Species.1 | Mouse |
| Gene ID.1 | 12527 |
| Uniprot.1 | P40240, |
| Species.2 | Rat |
| Gene ID.2 | 24936 |
| Uniprot.2 | P40241 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Membrane; Multi-pass membrane protein . Secreted, extracellular exosome . Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO. . |
| Tissue Expression | Detected in platelets (at protein level) (PubMed:19640571). Expressed by a variety of hematopoietic and epithelial cells (PubMed:19640571). |
| Signaling_pathway | Organismal Systems >> Immune system >> Hematopoietic cell lineage |
| Research Areas | >>Hematopoietic cell lineage |
| Function | Function:Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.,PTM:Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.,tissue specificity:Expressed by a variety of hematopoietic and epithelial cells., |
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