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Cdk11A/B Polyclonal Antibody
Product details
Background:
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
Specifications
| Size | 50μL/100μL |
| Target | Cdk11A/B |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 90kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from Cdk11A/B . at AA range: 190-270 |
| Specificity | Cdk11A/B Polyclonal Antibody detects endogenous levels of Cdk11A/B protein. |
| Gene Name | CDK11A/CDK11B |
| Protein Name | Cell division protein kinase 11A/B |
| Other Name | CDK11A; / CDC2L2; / CDC2L3; / PITSLREB; / Cyclin-dependent kinase 11A; / Cell division cycle 2-like protein kinase 2; / Cell division protein kinase 11A; / Galactosyltransferase-associated protein kinase p58/GTA; / PITSLRE serine/threonine-protein kinase C |
| Species | Human |
| Gene ID | 728642;984 |
| Uniprot | Q9UQ88;P21127 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm. Nucleus. |
| Tissue Expression | Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data., |
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