SKU: WP11559 Categories: ,

Cdk11A/B Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11559-100
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Product details

Background:

This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Specifications

Size50μL/100μL
TargetCdk11A/B
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)90kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from Cdk11A/B . at AA range: 190-270
SpecificityCdk11A/B Polyclonal Antibody detects endogenous levels of Cdk11A/B protein.
Gene NameCDK11A/CDK11B
Protein NameCell division protein kinase 11A/B
Other NameCDK11A; / CDC2L2; / CDC2L3; / PITSLREB; / Cyclin-dependent kinase 11A; / Cell division cycle 2-like protein kinase 2; / Cell division protein kinase 11A; / Galactosyltransferase-associated protein kinase p58/GTA; / PITSLRE serine/threonine-protein kinase C
SpeciesHuman
Gene ID728642;984
UniprotQ9UQ88;P21127
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm. Nucleus.
Tissue ExpressionExpressed ubiquitously. Some evidence of isoform-specific tissue distribution.
Signaling_pathway
Research Areas
FunctionCaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,
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