Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human CENPB
Specificity
This antibody detects endogenous levels of CENPB at Human, Mouse
Gene Name
CENPB
Protein Name
Major centromere autoantigen B (Centromere protein B) (CENP-B)
Other Name
Species
Human
Gene ID
1059
Uniprot
P07199,
Species.1
Mouse
Gene ID.1
12616
Uniprot.1
P27790
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Chromosome, centromere .
Tissue Expression
Signaling_pathway
Research Areas
Function
Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box . May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes (Probable).