Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human Centrin 3
Specificity
This antibody detects endogenous levels of Centrin 3 at Human, Mouse
Gene Name
CETN3 CEN3
Protein Name
Centrin-3
Other Name
Species
Human
Gene ID
1070
Uniprot
O15182,
Species.1
Mouse
Gene ID.1
12626
Uniprot.1
O35648
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nucleolus . Nucleus envelope . Nucleus, nuclear pore complex . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Centrosome of interphase and mitotic cells (PubMed:9256449). Localizes to centriole distal lumen (PubMed:26337392). Localization at the nuclear pore complex requires NUP153 and TPR (PubMed:23591820). .
Tissue Expression
Signaling_pathway
Research Areas
Function
Plays a fundamental role in microtubule-organizing center structure and function.; As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.