SKU: WP17435 Categories: ,

CETN2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17435-100
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Product details

Background:

Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCETN2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)19kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human CETN2 AA range: 1-51
SpecificityThis antibody detects endogenous levels of CETN2 at Human/Mouse
Gene NameCETN2 CALT CEN2
Protein NameCETN2
Other Name
SpeciesHuman
Gene ID1069
UniprotP41208,
Species.1Mouse
Gene ID.126370
Uniprot.1Q9R1K9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Nucleus envelope . Nucleus, nuclear pore complex . Nucleus .
Tissue Expression
Signaling_pathway
Research Areas>>Nucleotide excision repair
FunctionFunction:Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110.,miscellaneous:Binds two moles of calcium per mole of protein.,similarity:Belongs to the centrin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Centrosome of S-phase, interphase and mitotic cells.,subunit:Monomer. Interacts with CEP110, SFI1 and with XPC.,
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