CETN2 rabbit pAb
Product details
Background:
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CETN2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 19kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CETN2 AA range: 1-51 |
| Specificity | This antibody detects endogenous levels of CETN2 at Human/Mouse |
| Gene Name | CETN2 CALT CEN2 |
| Protein Name | CETN2 |
| Other Name | |
| Species | Human |
| Gene ID | 1069 |
| Uniprot | P41208, |
| Species.1 | Mouse |
| Gene ID.1 | 26370 |
| Uniprot.1 | Q9R1K9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Nucleus envelope . Nucleus, nuclear pore complex . Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Nucleotide excision repair |
| Function | Function:Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110.,miscellaneous:Binds two moles of calcium per mole of protein.,similarity:Belongs to the centrin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Centrosome of S-phase, interphase and mitotic cells.,subunit:Monomer. Interacts with CEP110, SFI1 and with XPC., |
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