ChemR23 Polyclonal Antibody
Ucallm_WP11614-50
Price range: $268.00 through $328.00
Product details
Background:
developmental stage:Expressed during bone development., function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2)., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.,
Specifications
| Size | 50μL/100μL |
| Target | ChemR23 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 42kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270 |
| Specificity | ChemR23 Polyclonal Antibody detects endogenous levels of ChemR23 protein. |
| Gene Name | CMKLR1 |
| Protein Name | Chemokine-like receptor 1 |
| Other Name | CMKLR1; / CHEMR23; / DEZ; / Chemokine-like receptor 1; / G-protein coupled receptor ChemR23; / G-protein coupled receptor DEZ |
| Species | Human |
| Gene ID | 1240 |
| Uniprot | Q99788, |
| Species.1 | Mouse |
| Gene ID.1 | 14747 |
| Uniprot.1 | P97468, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | O35786 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Internalizes efficiently in response to RARRES2. . |
| Tissue Expression | Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed during bone development.,Function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands., |
Please login to post questions
Related products
