SKU: WP4169 Categories: ,

CHIC2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4169-100
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Product details

Background:

This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCHIC2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)18kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human CHIC2 AA range: 111-161
SpecificityThis antibody detects endogenous levels of CHIC2 at Human/Mouse
Gene NameCHIC2 BTL
Protein NameCHIC2
Other Name
SpeciesHuman
Gene ID26511
UniprotQ9UKJ5,
Species.1Mouse
Gene ID.174277
Uniprot.1Q9D9G3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane . Cytoplasmic vesicle . Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Tissue Expression
Signaling_pathway
Research Areas
FunctionDisease:A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4; 12)(q12; p13) with ETV6.,PTM:Palmitoylation in the CHIC motif is required for membrane association.,similarity:Belongs to the CHIC family.,subcellular location:Also present at a Golgi-like vesicular compartment and at scattered vesicles.,
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