CHRAC15 Polyclonal Antibody
Ucallm_WP11625-50
Price range: $268.00 through $328.00
Product details
Background:
CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004],
Specifications
| Size | 50μL/100μL |
| Target | CHRAC15 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 15kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CHRC1. AA range:81-130 |
| Specificity | CHRAC15 Polyclonal Antibody detects endogenous levels of CHRAC15 protein. |
| Gene Name | CHRAC1 |
| Protein Name | Chromatin accessibility complex protein 1 |
| Other Name | CHRAC1; / CHRAC15; / Chromatin accessibility complex protein 1; / CHRAC-1; / Chromatin accessibility complex 15 kDa protein; / CHRAC-15; / HuCHRAC15; / DNA polymerase epsilon subunit p15 |
| Species | Human |
| Gene ID | 54108 |
| Uniprot | Q9NRG0, |
| Species.1 | Mouse |
| Gene ID.1 | 93696 |
| Uniprot.1 | Q9JKP8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Signaling_pathway | Genetic Information Processing >> Chromosome >> ATP-dependent chromatin remodeling |
| Research Areas | |
| Function | Function:Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.,subunit:Interacts with POLE3. Together with POLE3, ACF1 and ISWI/SNF2H proteins, it forms the ISWI chromatin-remodeling complex, CHRAC.,tissue specificity:Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas., |
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