Price range: $268.00 through $328.00
Background:
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
| Size | 50μL/100μL |
| Target | CL16A |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 116kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human CL16A AA range: 129-179 |
| Specificity | This antibody detects endogenous levels of CL16A at Human/Mouse |
| Gene Name | CLEC16A KIAA0350 |
| Protein Name | CL16A |
| Other Name | |
| Species | Human |
| Gene ID | 23274 |
| Uniprot | Q2KHT3, |
| Species.1 | Mouse |
| Gene ID.1 | 74374 |
| Uniprot.1 | Q80U30 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endosome membrane; Peripheral membrane protein . Lysosome membrane; Peripheral membrane protein . Associates with the endolysosome membrane. . |
| Tissue Expression | Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:Defects in CLEC16A might be a cause of insulin-dependent diabetes mellitus (IDDM) [MIM:222100].,similarity:Belongs to the CLEC16A/gop-1 family.,tissue specificity:Almost exclusively expressed in immune cells, including dendritic cells, B lymphocytes and natural killer cells., |
