SKU: WP11680 Categories: ,

CLLD7 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11680-100
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Product details

Background:

This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCLLD7
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)58kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RCBTB1. AA range:251-300
SpecificityCLLD7 Polyclonal Antibody detects endogenous levels of CLLD7 protein.
Gene NameRCBTB1
Protein NameRCC1 and BTB domain-containing protein 1
Other NameRCBTB1; / CLLD7; / E4.5; / RCC1 and BTB domain-containing protein 1; / Chronic lymphocytic leukemia deletion region gene 7 protein; / CLL deletion region gene 7 protein; / Regulator of chromosome condensation and BTB domain-containing protein 1
SpeciesHuman
Gene ID55213
UniprotQ8NDN9,
Species.1Mouse
Gene ID.171330
Uniprot.1Q6NXM2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionUbiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781).
Signaling_pathway
Research Areas
FunctionFunction:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed.,
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