Price range: $268.00 through $328.00
Background:
catalytic activity:Nucleoside 2′, 3′-cyclic phosphate + H(2)O = nucleoside 2′-phosphate., similarity:Belongs to the cyclic nucleotide phosphodiesterase family., subcellular location:Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
| Size | 50μL/100μL |
| Target | CNPase |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 47kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CNPase. AA range:59-108 |
| Specificity | CNPase Polyclonal Antibody detects endogenous levels of CNPase protein. |
| Gene Name | CNP |
| Protein Name | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
| Other Name | CNP; / 2'; / 3'-cyclic-nucleotide 3'-phosphodiesterase; / CNP; / CNPase |
| Species | Human |
| Gene ID | 1267 |
| Uniprot | P09543, |
| Species.1 | Mouse |
| Gene ID.1 | 12799 |
| Uniprot.1 | P16330, |
| Species.2 | Rat |
| Gene ID.2 | 25275 |
| Uniprot.2 | P13233 |
| Cellular Localization | Membrane; Lipid-anchor . Melanosome . Firmly bound to membrane structures of brain white matter. . |
| Tissue Expression | Brain,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 2'-phosphate.,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,subcellular location:Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV., |
