Name: CNT2 Polyclonal Antibody
SKU: WP11703
Price: 268 USD
Availability: InStock

CNT2 Polyclonal Antibody

Ucallm_WP11703-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP11703-100

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Product details

Background:

enzyme regulation:Inhibited by formycin B., function:Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues., similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family., tissue specificity:Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.,

Specifications

Size	50μL/100μL
Target	CNT2
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	65kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human SLC28A2. AA range:371-420
Specificity	CNT2 Polyclonal Antibody detects endogenous levels of CNT2 protein.
Gene Name	SLC28A2
Protein Name	Sodium/nucleoside cotransporter 2
Other Name	SLC28A2; / CNT2; / Sodium/nucleoside cotransporter 2; / Concentrative nucleoside transporter 2; / CNT 2; / hCNT2; / Na; / +; / /nucleoside cotransporter 2; / Sodium-coupled nucleoside transporter 2; / Sodium/purine nucleoside co-transporter; / SPNT; / Solute carrier
Species	Human
Gene ID	9153
Uniprot	O43868,
Species.1	Mouse
Gene ID.1
Uniprot.1	O88627,
Species.2	Rat
Gene ID.2	60423
Uniprot.2	Q62773
Cellular Localization	Membrane; Multi-pass membrane protein .
Tissue Expression	Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain (PubMed:9435697). Weak expression in lung (PubMed:9435697).
Signaling_pathway
Research Areas
Function	enzyme regulation:Inhibited by formycin B.,Function:Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.,similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.,