COL19A1 Polyclonal Antibody
Ucallm_WP11716-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | COL19A1 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 120kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Collagen XIX alpha1. AA range:421-470 |
| Specificity | COL19A1 Polyclonal Antibody detects endogenous levels of COL19A1 protein. |
| Gene Name | COL19A1 |
| Protein Name | Collagen alpha-1(XIX) chain |
| Other Name | COL19A1; / Collagen alpha-1; / XIX; / chain; / Collagen alpha-1; / Y; / chain |
| Species | Human |
| Gene ID | 1310 |
| Uniprot | Q14993, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q0VF58 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix . |
| Tissue Expression | Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord. |
| Signaling_pathway | |
| Research Areas | >>Protein digestion and absorption |
| Function | Domain:The numerous interruptions in the triple helix may make this molecule either elastic or flexible.,Function:May act as a cross-bridge between fibrils and other extracellular matrix molecules. Involved in skeletal myogenesis in the developing esophagus. May play a role in organization of the pericellular matrix or the sphinteric smooth muscle.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,subunit:Oligomer; disulfide-linked.,tissue specificity:Localized to vascular, neuronal, mesenchymal, and some epithelial basement membrane zones in umbilical cord., |
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