Price range: $268.00 through $328.00
Background:
copine 8(CPNE8) Homo sapiens Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | Copine 8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 65kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CPNE8. AA range:11-60 |
| Specificity | Copine 8 Polyclonal Antibody detects endogenous levels of Copine 8 protein. |
| Gene Name | CPNE8 |
| Protein Name | Copine-8 |
| Other Name | CPNE8; / Copine-8; / Copine VIII |
| Species | Human |
| Gene ID | 144402 |
| Uniprot | Q86YQ8, |
| Species.1 | Mouse |
| Gene ID.1 | 66871 |
| Uniprot.1 | Q9DC53 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | extracellular exosome, |
| Tissue Expression | Brain,Hippocampus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the copine family.,similarity:Contains 1 VWFA domain.,similarity:Contains 2 C2 domains., |
