SKU: WP11876 Categories: ,

CYP26C1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11876-100
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Product details

Background:

cytochrome P450 family 26 subfamily C member 1(CYP26C1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCYP26C1
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)57kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; WB 1:1000-1:5000; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CYP26C1. AA range:41-90
SpecificityCYP26C1 Polyclonal Antibody detects endogenous levels of CYP26C1 protein.
Gene NameCYP26C1
Protein NameCytochrome P450 26C1
Other NameCYP26C1; / Cytochrome P450 26C1
SpeciesHuman
Gene ID340665
UniprotQ6V0L0
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Single-pass membrane protein .
Tissue ExpressionDetected in most tissues at very low level.
Signaling_pathway
Research Areas>>Retinol metabolism; / >>Metabolic pathways
Functioncofactor:Heme group.,Function:Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).,induction:By retinoic acid.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Detected in most tissues at very low level.,
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