CYP26C1 Polyclonal Antibody
Ucallm_WP11876-50
Price range: $268.00 through $328.00
Product details
Background:
cytochrome P450 family 26 subfamily C member 1(CYP26C1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CYP26C1 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 57kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; WB 1:1000-1:5000; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CYP26C1. AA range:41-90 |
| Specificity | CYP26C1 Polyclonal Antibody detects endogenous levels of CYP26C1 protein. |
| Gene Name | CYP26C1 |
| Protein Name | Cytochrome P450 26C1 |
| Other Name | CYP26C1; / Cytochrome P450 26C1 |
| Species | Human |
| Gene ID | 340665 |
| Uniprot | Q6V0L0 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass membrane protein . |
| Tissue Expression | Detected in most tissues at very low level. |
| Signaling_pathway | |
| Research Areas | >>Retinol metabolism; / >>Metabolic pathways |
| Function | cofactor:Heme group.,Function:Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).,induction:By retinoic acid.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Detected in most tissues at very low level., |
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