Cystatin SA Polyclonal Antibody
Ucallm_WP11924-50
Price range: $268.00 through $328.00
Product details
Background:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | Cystatin SA |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 20kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CST2. AA range:11-60 |
| Specificity | Cystatin SA Polyclonal Antibody detects endogenous levels of Cystatin SA protein. |
| Gene Name | CST2 |
| Protein Name | Cystatin-SA |
| Other Name | CST2; / Cystatin-SA; / Cystatin-2; / Cystatin-S5 |
| Species | Human |
| Gene ID | 1470 |
| Uniprot | P09228 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in submandibular gland and parotid gland. |
| Signaling_pathway | |
| Research Areas | >>Salivary secretion |
| Function | Function:Thiol protease inhibitor.,similarity:Belongs to the cystatin family.,tissue specificity:Only expressed in submandibular gland and parotid gland., |
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