D106A rabbit pAb
Ucallm_WP17280-50
Price range: $268.00 through $328.00
Product details
Background:
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014],
Specifications
| Size | 50μL/100μL |
| Target | D106A |
| Reactivity | Human |
| Applications | IHC, IF |
| MW(Calculated) | 7kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human D106A AA range: 1-51 |
| Specificity | This antibody detects endogenous levels of D106A at Human |
| Gene Name | DEFB106A BD6 DEFB106 DEFB6; DEFB106B |
| Protein Name | D106A |
| Other Name | |
| Species | Human |
| Gene ID | 245909 |
| Uniprot | Q8N104 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). . |
| Tissue Expression | Expressed specifically in epididymis and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Has antibacterial activity.,similarity:Belongs to the beta-defensin family.,tissue specificity:Expressed specifically in epididymis and lung., |
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