SKU: WP11957 Categories: ,

DBC-1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11957-100
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Product details

Background:

tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,

Specifications

Size50μL/100μL
TargetDBC1
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)102kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:20000; IF 1:50-200
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human KIAA1967. AA range:431-480
SpecificityDBC-1 Polyclonal Antibody detects endogenous levels of DBC-1 protein.
Gene NameKIAA1967 DBC1
Protein NameDBIRD complex subunit KIAA1967
Other NameKIAA1967; / DBC1; / DBIRD complex subunit KIAA1967; / Deleted in breast cancer gene 1 protein; / DBC-1; / DBC.1; / p30 DBC
SpeciesHuman
Gene ID57805
UniprotQ8N163,
Species.1Mouse
Gene ID.1219158
Uniprot.1Q8VDP4
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
Tissue ExpressionExpressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
Signaling_pathwayEnvironmental Information Processing >> Signal transduction >> Wnt signaling pathway
Research Areas
Functiontissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
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