tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
Specifications
Size
50μL/100μL
Target
DBC1
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)
102kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human KIAA1967. AA range:431-480
Specificity
DBC-1 Polyclonal Antibody detects endogenous levels of DBC-1 protein.
Gene Name
KIAA1967 DBC1
Protein Name
DBIRD complex subunit KIAA1967
Other Name
KIAA1967; / DBC1; / DBIRD complex subunit KIAA1967; / Deleted in breast cancer gene 1 protein; / DBC-1; / DBC.1; / p30 DBC
Species
Human
Gene ID
57805
Uniprot
Q8N163,
Species.1
Mouse
Gene ID.1
219158
Uniprot.1
Q8VDP4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
Tissue Expression
Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
Signaling_pathway
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Research Areas
Function
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,