Background:
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
Specifications
Size
50μL/100μL
Target
DBC1
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, ICC, IP
MW(Calculated)
MW(Observed)
130kD
Host Species
Mouse
Isotype
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500; ICC 1:200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality
Monoclonal
Clone Number
15B4
Immunogen
Purified recombinant human DBC1 protein fragments expressed in E.coli
Specificity
This antibody detects endogenous levels of DBC1 and does not cross-react with related proteins
Gene Name
KIAA1967 DBC1
Protein Name
Other Name
DBCCR1; / Deleted in bladder cancer protein 1; / Deleted in bladder cancer protein 1 recursor; / FAM5A; / Protein FAM5A.
Species
Human
Gene ID
57805
Uniprot
Q8N163,
Species.1
Mouse
Gene ID.1
219158
Uniprot.1
Q8VDP4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
Tissue Expression
Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
Signaling_pathway
Environmental Information Processing >> Signal transduction >> Wnt signaling pathway
Research Areas
Function
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,