DHA Kinase Polyclonal Antibody
Ucallm_WP12003-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4', 5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | DHA Kinase |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 59kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:200-1:1000; ELISA 1:20000; IF 1:20-50 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DAK. AA range:91-140 |
| Specificity | DHA Kinase Polyclonal Antibody detects endogenous levels of DHA Kinase protein. |
| Gene Name | DAK |
| Protein Name | Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase |
| Other Name | DAK; / Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase; / cyclizing |
| Species | Human |
| Gene ID | 26007 |
| Uniprot | Q3LXA3, |
| Species.1 | Mouse |
| Gene ID.1 | 225913 |
| Uniprot.1 | Q8VC30, |
| Species.2 | Rat |
| Gene ID.2 | 361730 |
| Uniprot.2 | Q4KLZ6 |
| Cellular Localization | nucleus,cytosol,extracellular exosome, |
| Tissue Expression | Detected in erythrocytes (at protein level). |
| Signaling_pathway | Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway |
| Research Areas | >>Fructose and mannose metabolism; / >>Glycerolipid metabolism; / >>Metabolic pathways; / >>Carbon metabolism; / >>RIG-I-like receptor signaling pathway |
| Function | Catalytic activity:ATP + glycerone = ADP + glycerone phosphate.,Catalytic activity:FAD = AMP + riboflavin cyclic-4',5'-phosphate.,cofactor:Magnesium.,cofactor:Manganese or cobalt; for FAD-AMP lyase activity.,enzyme regulation:Each activity is inhibited by the substrate(s) of the other.,Function:Catalyzes both the phosphorylation of dihydroxyacetone and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate.,similarity:Belongs to the dihydroxyacetone kinase (DAK) family.,similarity:Contains 1 DAK1 (dihydroxyacetone kinase subunit 1) domain.,similarity:Contains 1 DAK2 (dihydroxyacetone kinase subunit 2) domain.,subunit:Homodimer., |
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