Chitobiase is a lysosomal glycosidase involved in degradation of asparagine-linked oligosaccharides on glycoproteins (Aronson and Kuranda, 1989 [PubMed 2531691]).[supplied by OMIM, Nov 2010],
Specifications
Size
50μL/100μL
Target
DIAC
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
42kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
DIAC Polyclonal Antibody detects endogenous levels of protein.
Gene Name
CTBS CTB
Protein Name
Di-N-acetylchitobiase (EC 3.2.1.-)
Other Name
Species
Human
Gene ID
1486
Uniprot
Q01459,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8R242,
Species.2
Rat
Gene ID.2
Uniprot.2
Q01460
Cellular Localization
Lysosome.
Tissue Expression
Brain,Liver,Placenta,Testis,
Signaling_pathway
Research Areas
Function
Function:Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.,similarity:Belongs to the glycosyl hydrolase 18 family.,