SKU: WP1196 Categories: ,

DLX1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1196-100
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Product details

Background:

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetDLX1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)28kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityDLX1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameDLX1
Protein NameHomeobox protein DLX-1
Other Name
SpeciesHuman
Gene ID1745
UniprotP56177,
Species.1Mouse
Gene ID.1
Uniprot.1Q64317,
Species.2Rat
Gene ID.2
Uniprot.2Q64202
Cellular LocalizationNucleus .
Tissue ExpressionExpressed in hematopoietic cell lines.
Signaling_pathway
Research Areas
FunctionFunction:Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions.,similarity:Belongs to the distal-less homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
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