Product details
Background:
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DIS3L rabbit pAb
Ucallm_WP8116-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DIS3L |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 116kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DIS3L |
| Specificity | This antibody detects endogenous levels of DIS3L at Human, Mouse,Rat |
| Gene Name | DIS3L DIS3L1 KIAA1955 |
| Protein Name | DIS3-like exonuclease 1 (EC 3.1.13.-) |
| Other Name | |
| Species | Human |
| Gene ID | 115752 |
| Uniprot | Q8TF46, |
| Species.1 | Mouse |
| Gene ID.1 | 213550 |
| Uniprot.1 | Q8C0S1, |
| Species.2 | Rat |
| Gene ID.2 | 363077 |
| Uniprot.2 | Q5U2P0 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> RNA degradation |
| Research Areas | |
| Function | Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. |
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