SKU: WP6776 Categories: ,

DMXL2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6776-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetDMXL2
ReactivityHuman
ApplicationsWB
MW(Calculated)334kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human DMXL2
SpecificityThis antibody detects endogenous levels of DMXL2 at Human
Gene NameDMXL2 KIAA0856
Protein NameDmX-like protein 2 (Rabconnectin-3)
Other Name
SpeciesHuman
Gene ID23312
UniprotQ8TDJ6,
Species.1Mouse
Gene ID.1
Uniprot.1Q8BPN8
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle . The external layer of the inferior boundary for the hypothalamus part of the human brain (the so called median eminence (ME)) displayed a punctate pattern of expression; expression also observed in the cell bodies lining the third ventricle, in the long processes extending from these cell bodies toward the external layer of the ME, in small clear vesicles, and in large dense core vesicles. .
Tissue Expression
Signaling_pathwayCellular Processes >> Transport and catabolism >> Lysosome
Research Areas
FunctionMay serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles . Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes (By similarity).
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