Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human DMXL2
Specificity
This antibody detects endogenous levels of DMXL2 at Human
Gene Name
DMXL2 KIAA0856
Protein Name
DmX-like protein 2 (Rabconnectin-3)
Other Name
Species
Human
Gene ID
23312
Uniprot
Q8TDJ6,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8BPN8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle . The external layer of the inferior boundary for the hypothalamus part of the human brain (the so called median eminence (ME)) displayed a punctate pattern of expression; expression also observed in the cell bodies lining the third ventricle, in the long processes extending from these cell bodies toward the external layer of the ME, in small clear vesicles, and in large dense core vesicles. .
Tissue Expression
Signaling_pathway
Cellular Processes >> Transport and catabolism >> Lysosome
Research Areas
Function
May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles . Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes (By similarity).