DNASE2B rabbit pAb
Ucallm_WP7130-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | DNASE2B |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 40kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DNASE2B |
| Specificity | This antibody detects endogenous levels of DNASE2B at Human, Mouse,Rat |
| Gene Name | DNASE2B DLAD |
| Protein Name | Deoxyribonuclease-2-beta (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD) |
| Other Name | |
| Species | Human |
| Gene ID | 58511 |
| Uniprot | Q8WZ79, |
| Species.1 | Mouse |
| Gene ID.1 | 56629 |
| Uniprot.1 | Q9QY48, |
| Species.2 | Rat |
| Gene ID.2 | 59296 |
| Uniprot.2 | Q9QZK9 |
| Cellular Localization | Lysosome . |
| Tissue Expression | Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Lysosome;Organismal Systems >> Immune system >> Cytosolic DNA-sensing pathway |
| Research Areas | |
| Function | Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation. |
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