DPEP1 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | DPEP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 45kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DPEP1 |
| Specificity | This antibody detects endogenous levels of DPEP1 at Human, Mouse,Rat |
| Gene Name | DPEP1 MDP RDP |
| Protein Name | Dipeptidase 1 (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP) |
| Other Name | |
| Species | Human |
| Gene ID | 1800 |
| Uniprot | P16444, |
| Species.1 | Mouse |
| Gene ID.1 | 13479 |
| Uniprot.1 | P31428, |
| Species.2 | Rat |
| Gene ID.2 | 94199 |
| Uniprot.2 | P31430 |
| Cellular Localization | Apical cell membrane; Lipid-anchor, GPI-anchor . Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor . Brush border membrane. . |
| Tissue Expression | Expressed in lung and kidneys. |
| Signaling_pathway | |
| Research Areas | |
| Function | Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 . Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (By similarity). Possesses also beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics .; Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. |
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