SKU: WP12062 Categories: ,

DPF2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12062-100
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Product details

Background:

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetDPF2
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)44kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human REQU. AA range:151-200
SpecificityDPF2 Polyclonal Antibody detects endogenous levels of DPF2 protein.
Gene NameDPF2
Protein NameZinc finger protein ubi-d4
Other NameDPF2; / BAF45D; / REQ; / UBID4; / Zinc finger protein ubi-d4; / Apoptosis response zinc finger protein; / BRG1-associated factor 45D; / BAF45D; / D4; / zinc and double PHD fingers family 2; / Protein requiem
SpeciesHuman
Gene ID5977
UniprotQ92785,
Species.1Mouse
Gene ID.119708
Uniprot.1Q61103
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Cytoplasm .
Tissue ExpressionUbiquitous.
Signaling_pathwayGenetic Information Processing >> Chromosome >> ATP-dependent chromatin remodeling
Research Areas
FunctionFunction:May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.,similarity:Belongs to the requiem/DPF family.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 2 PHD-type zinc fingers.,subcellular location:30% nuclear. 70% cytoplasmic.,tissue specificity:Ubiquitous.,
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