DPPA5 Polyclonal Antibody
Product details
Background:
This gene encodes a protein that may function in the control of cell pluripotency and early embryogenesis. Expression of this gene is a specific marker for pluripotent stem cells. Pseudogenes of this gene are located on the short arm of chromosome 10 and the long arm of chromosomes 14 and 19. [provided by RefSeq, Dec 2010],
Specifications
| Size | 50μL/100μL |
| Target | DPPA5 |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 12kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 1-50 |
| Specificity | DPPA5 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | DPPA5 ESG1 |
| Protein Name | Developmental pluripotency-associated 5 protein (hDPPA5) (Embryonal stem cell-specific gene 1 protein) (ESG-1) |
| Other Name | |
| Species | Human |
| Gene ID | 340168 |
| Uniprot | A6NC42 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed in primordial germ (PGC), embryonic germ (EGC) and embryonic stem (ESC) cells. Not detected in embryonic carcinoma (ECC) cells.,Function:Involved in the maintenance of embryonic stem (ES) cell pluripotency. Dispensable for self-renewal of pluripotent ES cells and establishment of germ cells. Associates with specific target mRNAs.,induction:Down-regulated in differentiated embryonic stem (ESC) cells, compared with strong expression in undifferentiated ESC cells.,similarity:Belongs to the KHDC1 family.,similarity:Contains 1 KH domain., |
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