Product details
Background:
DPYL3 rabbit pAb
Ucallm_WP3586-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DPYL3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 65kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DPYL3 AA range: 240-290 |
| Specificity | This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat |
| Gene Name | DPYSL3 CRMP4 DRP3 ULIP ULIP1 |
| Protein Name | DPYL3 |
| Other Name | Dihydropyrimidinase-related protein 3; / DRP-3; / Collapsin response mediator protein 4; / CRMP-4; / Unc-33-like phosphoprotein 1; / ULIP-1 |
| Species | Human |
| Gene ID | 1809 |
| Uniprot | Q14195, |
| Species.1 | Mouse |
| Gene ID.1 | 22240 |
| Uniprot.1 | Q62188, |
| Species.2 | Rat |
| Gene ID.2 | 25418 |
| Uniprot.2 | Q62952 |
| Cellular Localization | Cytoplasm . Cell projection, growth cone . Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. . |
| Tissue Expression | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5 (By similarity). Interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.,tissue specificity:Mainly in heart and skeletal muscle. Also expressed strongly in fetal brain and spinal cord., |
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