Product details
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DR1 rabbit pAb
Ucallm_WP7475-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DR1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 19kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DR1 |
| Specificity | This antibody detects endogenous levels of DR1 at Human, Mouse,Rat |
| Gene Name | DR1 |
| Protein Name | Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein) |
| Other Name | |
| Species | Human |
| Gene ID | 1810 |
| Uniprot | Q01658, |
| Species.1 | Mouse |
| Gene ID.1 | 13486 |
| Uniprot.1 | Q91WV0, |
| Species.2 | Rat |
| Gene ID.2 | 100910207 |
| Uniprot.2 | Q5XI68 |
| Cellular Localization | Nucleus. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
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