Product details
Background:
DTX2 rabbit pAb
Ucallm_WP7085-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DTX2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 68kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DTX2 |
| Specificity | This antibody detects endogenous levels of DTX2 at Human, Mouse |
| Gene Name | DTX2 KIAA1528 RNF58 |
| Protein Name | Probable E3 ubiquitin-protein ligase DTX2 (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) |
| Other Name | |
| Species | Human |
| Gene ID | 113878 |
| Uniprot | Q86UW9, |
| Species.1 | Mouse |
| Gene ID.1 | 74198 |
| Uniprot.1 | Q8R3P2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. . |
| Tissue Expression | |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> Notch signaling pathway |
| Research Areas | |
| Function | Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |
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