Product details
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EDF1 rabbit pAb
Ucallm_WP7072-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | EDF1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 16kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EDF1 |
| Specificity | This antibody detects endogenous levels of EDF1 at Human, Mouse,Rat |
| Gene Name | EDF1 |
| Protein Name | Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1) |
| Other Name | |
| Species | Human |
| Gene ID | 8721 |
| Uniprot | O60869, |
| Species.1 | Mouse |
| Gene ID.1 | 59022 |
| Uniprot.1 | Q9JMG1, |
| Species.2 | Rat |
| Gene ID.2 | 296570 |
| Uniprot.2 | P69736 |
| Cellular Localization | Cytoplasm. Nucleus. Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin. |
| Tissue Expression | Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism. |
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