EHBP1 rabbit pAb
Ucallm_WP4460-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Specifications
| Size | 50μL/100μL |
| Target | EHBP1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 135kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EHBP1 AA range: 364-414 |
| Specificity | This antibody detects endogenous levels of EHBP1 at Human/Mouse |
| Gene Name | EHBP1 KIAA0903 NACSIN |
| Protein Name | EHBP1 |
| Other Name | |
| Species | Human |
| Gene ID | 23301 |
| Uniprot | Q8NDI1, |
| Species.1 | Mouse |
| Gene ID.1 | 216565 |
| Uniprot.1 | Q69ZW3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Membrane . Endosome . Mostly found in cytosol and plasma membrane. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A genetic variation in EHBP1 is associated with susceptibility to hereditary prostate cancer type 12 (HPC12) [MIM:611868].,Function:May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton.,sequence Caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 CH (calponin-homology) domain.,subcellular location:Mostly found in cytosol and plasma membrane.,subunit:Interacts with EHD2., |
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