Name: Elongin A3 Polyclonal Antibody
SKU: WP12162
Price: 268 USD
Availability: InStock

Elongin A3 Polyclonal Antibody

Ucallm_WP12162-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP12162-100

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Product details

Background:

The SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This complex is a heterotrimer, composed of the transcriptionally active subunit A, A2 or A3 (or elongin A, A2 or A3) and two regulatory subunits, B and C (or elongin B and C). This gene encodes subunit A3. A3 and A are ubiquitously expressed, whereas A2 is specifically expressed in the testis. [provided by RefSeq, Mar 2010],

Specifications

Size	50μL/100μL
Target	Elongin A3
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	60kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human ELOA3. AA range:381-430
Specificity	Elongin A3 Polyclonal Antibody detects endogenous levels of Elongin A3 protein.
Gene Name	TCEB3C
Protein Name	RNA polymerase II transcription factor SIII subunit A3
Other Name	TCEB3C; / TCEB3L2; / RNA polymerase II transcription factor SIII subunit A3; / Elongin-A3; / EloA3; / Transcription elongation factor B polypeptide 3C
Species	Human
Gene ID	162699
Uniprot	Q8NG57
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	integral component of membrane,elongin complex,
Tissue Expression
Signaling_pathway
Research Areas
Function	Domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x(3)-C-x(3)-[AILV].,Function:SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).,similarity:Contains 1 TFIIS N-terminal domain.,subunit:Heterotrimer of an A (A1, A2 or A3), B and C subunit.,tissue specificity:Widely expressed.,

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Elongin A3 Polyclonal Antibody

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Elongin A3 Polyclonal Antibody

Product details

Specifications

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