Endomucin Polyclonal Antibody
Ucallm_WP12183-50
Price range: $268.00 through $328.00
Product details
Background:
endomucin(EMCN) Homo sapiens EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008],
Specifications
| Size | 50μL/100μL |
| Target | Endomucin |
| Reactivity | Human, Mouse, Rat |
| Applications | IF, ELISA |
| MW(Calculated) | 27kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications; |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Mucin-14. AA range:201-250 |
| Specificity | Endomucin Polyclonal Antibody detects endogenous levels of Endomucin protein. |
| Gene Name | EMCN |
| Protein Name | Endomucin |
| Other Name | EMCN; / EMCN2; / MUC14; / Endomucin; / Endomucin-2; / Gastric cancer antigen Ga34; / Mucin-14; / MUC-14 |
| Species | Human |
| Gene ID | 51705 |
| Uniprot | Q9ULC0, |
| Species.1 | Mouse |
| Gene ID.1 | 59308 |
| Uniprot.1 | Q9R0H2, |
| Species.2 | Rat |
| Gene ID.2 | 295490 |
| Uniprot.2 | Q6AY82 |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.; [Isoform 2]: Secreted . |
| Tissue Expression | Expressed in heart, kidney and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.,PTM:Highly O-glycosylated. Sialic acid-rich glycoprotein.,subcellular location:Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.,tissue specificity:Expressed in heart, kidney and lung., |
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