Product details
Background:
ESPN rabbit pAb
Ucallm_WP8143-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ESPN |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 94kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ESPN |
| Specificity | This antibody detects endogenous levels of ESPN at Human, Mouse,Rat |
| Gene Name | ESPN DFNB36 LP2654 |
| Protein Name | Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein) |
| Other Name | |
| Species | Human |
| Gene ID | 83715 |
| Uniprot | B1AK53, |
| Species.1 | Mouse |
| Gene ID.1 | 56226 |
| Uniprot.1 | Q9ET47, |
| Species.2 | Rat |
| Gene ID.2 | 56227 |
| Uniprot.2 | Q63618 |
| Cellular Localization | Cytoplasm, cytoskeleton . Cell projection, stereocilium . Cell projection, microvillus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells . Required for the assembly and stabilization of the stereociliary parallel actin bundles. Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia (By similarity). Involved in the elongation of actin in stereocilia . In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation. |
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