PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.,
Specifications
Size
50μL/100μL
Target
ETAA1
Reactivity
Human, Mouse
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
101kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ETAA1 Polyclonal Antibody detects endogenous levels of protein.
Nucleus . Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720). .
Tissue Expression
Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.
Signaling_pathway
Research Areas
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.,