Product details
Background:
EXT2 rabbit pAb
Ucallm_WP8895-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | EXT2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 79kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EXT2 |
| Specificity | This antibody detects endogenous levels of EXT2 at Human, Mouse |
| Gene Name | EXT2 |
| Protein Name | Exostosin-2 (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2) |
| Other Name | |
| Species | Human |
| Gene ID | 2132 |
| Uniprot | Q93063, |
| Species.1 | Mouse |
| Gene ID.1 | 14043 |
| Uniprot.1 | P70428 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein . Golgi apparatus membrane; Single-pass type II membrane protein . Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein . The EXT1/EXT2 complex is localized in the Golgi apparatus. |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan . |
Please login to post questions
Related products
