EXTL2 rabbit pAb
Ucallm_WP16370-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | EXTL2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 36kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EXTL2 AA range: 141-191 |
| Specificity | This antibody detects endogenous levels of EXTL2 at Human/Mouse |
| Gene Name | EXTL2 EXTR2 |
| Protein Name | EXTL2 |
| Other Name | |
| Species | Human |
| Gene ID | 2135 |
| Uniprot | Q9UBQ6, |
| Species.1 | Mouse |
| Gene ID.1 | 58193 |
| Uniprot.1 | Q9ES89 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein .; [Processed exostosin-like 2]: Secreted. A soluble form is found in the serum. |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | >>Glycosaminoglycan biosynthesis - heparan sulfate / heparin; / >>Metabolic pathways |
| Function | Catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,Function:Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.,online information:Exostosin-like 2,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 47 family.,subcellular location:A soluble form is found in the serum.,tissue specificity:Ubiquitous., |
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