SKU: WP16460 Categories: ,

F8I2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16460-100
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Product details

Background:

This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb, and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h), containing F8A, is repeated twice extragenically closer to the Xq telomere. Although its function is unknown, the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetF8I2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)41kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human F8I2 AA range: 33-83
SpecificityThis antibody detects endogenous levels of F8I2 at Human/Mouse
Gene NameF8A1 F8A; F8A2 F8A; F8A3 F8A
Protein NameF8I2
Other Name
SpeciesHuman
Gene ID474383
UniprotP23610,
Species.1Mouse
Gene ID.1
Uniprot.1Q00558
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Nucleus . Early endosome . Nucleus, nuclear body . Diffuse presence in the cytoplasm and accumulation in the nucleus (PubMed:16476778). In absence of HTT, F8A1/F8A2/F8A3 is concentred in cytoplasm (By similarity). Colocalized with HTT in endosomes (PubMed:16476778). In neuron found in intranuclear structures, the intranuclear rodlets (INRs), also known as rodlets of Roncoroni, in association with ubiquitin (By similarity). .
Tissue ExpressionProduced abundantly in a wide variety of cell types.
Signaling_pathway
Research Areas
FunctionFunction:Not known. Possible housekeeping role.,tissue specificity:Produced abundantly in a wide variety of cell types.,
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