Price range: $268.00 through $328.00
Background:
function:Protects cells uniquely from Fas-induced apoptosis., similarity:Belongs to the BI1 family., subunit:Interacts with TNFRSF6., tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,
| Size | 50μL/100μL |
| Target | FAIM2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 35kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from the N-terminal region of human FAIM2. |
| Specificity | FAIM2 Polyclonal Antibody detects endogenous levels of FAIM2 protein. |
| Gene Name | FAIM2 |
| Protein Name | Protein lifeguard 2 |
| Other Name | FAIM2; / KIAA0950; / LFG; / LFG2; / NMP35; / TMBIM2; / Protein lifeguard 2; / Fas apoptotic inhibitory molecule 2; / Neural membrane protein 35; / Transmembrane BAX inhibitor motif-containing protein 2 |
| Species | Human |
| Gene ID | 23017 |
| Uniprot | Q9BWQ8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8K097 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Membrane raft . Cell junction, synapse, postsynaptic cell membrane . |
| Tissue Expression | Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus., |
