FAM92A1 rabbit pAb
Ucallm_WP6947-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | CIBAR1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 32kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FAM92A1 |
| Specificity | This antibody detects endogenous levels of FAM92A1 at Human, Mouse |
| Gene Name | FAM92A1 |
| Protein Name | Protein FAM92A1 |
| Other Name | |
| Species | Human |
| Gene ID | 137392 |
| Uniprot | A1XBS5, |
| Species.1 | Mouse |
| Gene ID.1 | 68099 |
| Uniprot.1 | Q8BP22 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Cell projection, cilium . Nucleus . Mitochondrion inner membrane; Peripheral membrane protein; Matrix side . Weak punctate vesicular distribution throughout the cytoplasm (PubMed:27528616). Localizes at the distal end of mother centrioles (PubMed:27528616). Extensive colocalization with CBY1 at mother centrioles (PubMed:27528616). .; [Isoform 3]: Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as a positive regulator of ciliary hedgehog signaling (By similarity). Probable regulator of ciliogenesis involved in limb morphogenesis . In cooperation with CBY1 it is involved in the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis . Plays an important role in the mitochondrial function and is essential for maintaining mitochondrial morphology and inner membrane ultrastructure . In vitro, can generate membrane curvature through preferential interaction with negatively charged phospholipids such as phosphatidylinositol 4,5-bisphosphate and cardiolipin and hence orchestrate cristae shape . |
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