Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human FANCC
Specificity
This antibody detects endogenous levels of FANCC at Human,Rat
Gene Name
FANCC FAC FACC
Protein Name
Fanconi anemia group C protein (Protein FACC)
Other Name
Species
Human
Gene ID
2176
Uniprot
Q00597,
Species.1
Mouse
Gene ID.1
Uniprot.1
P50652,
Species.2
Rat
Gene ID.2
Uniprot.2
O35870
Cellular Localization
Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
Tissue Expression
Ubiquitous.
Signaling_pathway
Research Areas
Function
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.