SKU: WP12282 Categories: ,

FASTKD3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12282-100
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Product details

Background:

This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],

Specifications

Size50μL/100μL
TargetFASTKD3
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)75kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human FAKD3. AA range:121-170
SpecificityFASTKD3 Polyclonal Antibody detects endogenous levels of FASTKD3 protein.
Gene NameFASTKD3
Protein NameFAST kinase domain-containing protein 3
Other NameFASTKD3; / FAST kinase domain-containing protein 3
SpeciesHuman
Gene ID79072
UniprotQ14CZ7,
Species.1Mouse
Gene ID.1
Uniprot.1Q8BSN9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion .
Tissue ExpressionExpression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the FAST kinase family.,similarity:Contains 1 RAP domain.,
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